Description
FOXO4-DRI (10 mg) High-Purity Research Compound | For Laboratory Use Only
FOXO4-DRI (also known as FOXO4-D-Retro-Inverso) is a synthetic cell-permeable peptide designed to disrupt the interaction between FOXO4 and p53 proteins. Researchers use it as a senolytic tool to study the selective clearance of senescent (“zombie”) cells in aging and disease models.
In laboratory experiments, scientists use FOXO4-DRI to explore:
- Selective elimination of senescent cells
- Cellular aging and senescence pathways
- Tissue regeneration and rejuvenation processes
- Inflammation reduction linked to senescent cell burden
- Age-related decline in various organ systems
- Potential synergies with other senolytic approaches
As a D-amino acid retro-inverso peptide, FOXO4-DRI is highly stable and can enter cells effectively, allowing researchers to investigate apoptosis (programmed cell death) specifically in senescent cells while sparing healthy ones in preclinical models.
Why Researchers Choose FOXO4-DRI
This peptide is a leading tool in modern senolytic and longevity research because of its targeted ability to address one of the hallmarks of aging.
• Senolytic Activity Selectively induces apoptosis in senescent cells by blocking FOXO4-p53 interaction.
• Anti-Aging Research Focus Widely studied for its potential to improve tissue function and reduce age-related inflammation.
• High Stability D-retro-inverso design provides excellent stability and cell permeability.
• Valuable in Multiple Models Used in studies on aging, osteoarthritis, frailty, and other senescence-related conditions.
• High Purity You Can Trust PuraNova Labs supplies consistent ≥99% pure material for reliable, reproducible research results.
Important Notice: PuraNova Labs provides FOXO4-DRI strictly for research and laboratory use only. This product is intended for qualified researchers and institutions. It is not for human consumption, medical use, therapeutic purposes, or veterinary applications.
Product Details
- Compound: FOXO4-DRI (FOXO4 D-Retro-Inverso peptide)
- Purity: ≥99% (third-party tested)
- Format: Lyophilized powder (10 mg)
- Storage: Store in a cool, dry place. Follow standard laboratory handling procedures.
- CAS Number: 2460055-10-9
- Molecular Weight: 5358 g/mol
- Appearance: White to off-white powder
Current Pricing:
Single: $175
3-Vial Bundle: $285
5-Vial Bundle: $425
10-Vial Bundle: $745
Research Use Only:
Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.




